News

As Scientists, we have the unique opportunity of inspiring critical thinking and dialogue in the Society. Our efforts in communication can foster the understanding of novel and complex discoveries, which are of fundamental importance for societal development. Moreover, our obligation to the public is in explaining the stewardship of the public funds used to support us.


Anticancer drug gets a boost when combined with antirheumatic 

ciao

Molecular dynamics and X-ray crystallography have discovered that combining an anticancer drug with an antirheumatic produces improved effects against tumors. The discovery opens a new path for drug-drug synergy. 

    Read more:        Science Daily       20min


 Supercomputers reveal acrobatics of CRISPR-Cas9

Read more:        UCSD news     


The RNA that snips and stitches RNA

shapeimage_2
Credit: Lorenzo Casalino (SISSA)

2016, July. This press release highlights our recent study published on the Journal of the American chemical Society, on the splicing mechanism in GroupII intron, the ancestor of the Human Spliceosome, which is the fundamental machinery allowing the maturation of RNA for subsequent gene expression.

This research has been possible thanks to the partnership between Profs. A. Magistrato (SISSA) and U. Roethlisberger (EPFL). 

    Read more:        Science Newsline Biology        Science Daily


Metal Drugs to Fight Cancer

shapeimage_2-2
2015, December. Novel anticancer drugs arising from the collaboration between 
EPFL (Switzerland), NTU (Singapore) and SISSA (Italy). 

Read more:       Science Daily         Medical Xpress        TrendSoul               


The Invisible Dance of a Drug

2015, March. Our work (De Vivo labIIT) on pharmaceutically relevant metalloenzymes has been reported by the renown Italian newspaper “Il sole 24 ore” in the article entitled “The invisible dance of a drug”where we describe the use of supercomputers for the discovery of new drugs targeting cancer.